مجله‌ي بین المللی غدد درون‌ريز و متابوليسمInt J Endocrinol MetabMedical Scienceshttp://www.ijem.org1726-913XenBone Mineral Density at Lumbar Spine and Femur. An Epidemiological Study in the Athens Metropolitan Area, GreeceLegakis I^a, Papadopoulos V^b, Tataridas V^b, Strigaris K^bLegakis I^a Papadopoulos V<sup>b</sup> Tataridas V<sup>b</sup> Strigaris K<sup>b</sup><sup>a</sup>Departments of Endocrinology and <sup>b</sup>Radiology, Henry Dunant Hospital, Athens, Greece Original ArticleWe aimed at determining the prevalence of osteoporosis and osteopenia in an urban population. Materials and Methods: DXA measurements were done at the lumbar spine (4914 females, aged 50 to 93 years and 111 males, aged 50-89) and at the femur (2943 females, aged 50-95 and 105 males, aged 51-92). Bone mineral density (BMD) and corresponding T-scores were analysed using multivariate regression models. Results: In females, the prevalence rate of osteo-porosis was 19.56% (95% confidence interval (CI):18.46/20.69) at the lumbar spine and of os-teopenia 41.68% (95% CI: 40.29/43.07). The cor-responding numbers in males were 16.22 % (95% CI: 9.90/24.41) and 33.33% (95% CI: 24.67/42.91). In females osteoporosis rate at the femur was 18.99% (95% CI: 17.59/20.46) for the neck and 2.0% (95% CI: 1.53/2.58) for the tronchater, whe-reas the osteopenic rates were 54.57% (95% CI: 52.75/56.38) and 32.38% (95% CI:30.69/34.11) re-spectively. In males, osteoporosis rate at the fe-mur was 38.10% (95% CI: 28.79/48.09) for the neck and 13.33% (95% CI: 7.49/21.36) for the tron-chater, whereas the corresponding osteopenic rates were 46.67% (95% CI: 36.87/56.66) and 41.90% (95% CI: 32.34/51.93). A polynominal cu-bic model performed for age showed the steepest decline at the age of 55 years for the spine BMD (-0.973% change, 95% CI -1.031/-0.915) and at the age of 64 years for the femur BMD (-0.726% change, 95% CI -0.793/-0.658). Conclusion: Sensitive interventions and strate-gies for prevention of osteoporosis in urban populations need to be designed and imple-mentted.Osteporosis, Osteopenia, Bone mineral density, Dual energy X-ray absorptiometry, T-score, Spine, Femur, Urban populationBone Mineral Density in Athens Ioannis Legakis2/17/2009 12:00:00 AM4/4/2009 12:00:00 AMilegak@med.uoa.gr275666http://www.ijem.org/Default.aspx